Oct 13, 2012 · Mass Effect: Paragon Lost takes place during the events of Mass Effect 2 and serve as the backstory for James Vega (who does not appear in the games until 3). While it is possible to understand what is going on in Paragon Lost without a knowledge of the games, having this knowledge is beneficial since you won’t have to grasp onto every bit of 3/5(704). The Mass Effect series has so far spawned three games, a bunch of DLC, some acceptable expanded universe novels, comics, a couple of fan-films, and a possible feature film. It also gave us Mass Effect: Paragon Lost.2.2/5(23). Mass Effect: Paragon Lost Synopsis. Alliance Marine James Vega leads a squad of elite soldiers in a battle against an alien threat. Read Full Synopsis Cast + Crew Previous Cast Members More Cast Members. See Full Cast + Crew for Mass Effect: Paragon Lost Features Load More Features 57%(67).